0. Mesothelioma, Bruce W. S. Robinson MD, A. Philippe Chahinian, MARTIN DUNITZ; 2002
1. Wagner, J.C., Sleggs, C.A., Marchand, P. Diffuse pleural mesothelioma and asbestos expo-
sure in the North Western Cape Province. Br J Ind Med 1960; 17: 260–271.
2. Hansen, J., Deklerk, N.H., Musk, A.W., Hobbs, M.S.T. Environmental exposure to crocido-
lite and mesothelioma – exposure-response relationships. Am J Respir Crit Care Med 1998;
157: 69–75.
3. McDonald, J.C., McDonald, A.D. The epidemiology of mesothelioma in historical context [Review]. Eur Respir J 1996; 9: 1932–1942.
4. Branchaud, R.M., Garant, L.J., Kane, A.B. Pathogenesis of mesothelial reactions to asbes-
tos fibres. Monocyte recruitment and macrophage activation. Pathobiology 1993; 61: 154–
163.
5. Owens, M.W., Grimes, S.R. Pleural mesothelial cell response to inflammation: tumor ne-
crosis factor-induced mitogenesis and collagen synthesis. Am J Physiol 1993; 265: L382–
388.
6. Davis, J.M. Ultrastructure of human mesotheliomas. J Natl Cancer Inst 1974; 52: 1715–
1725.
7. Mossman, B.T., Marsh, J.P. Evidence supporting a role for active oxygen species in asbes-
tos-induced toxicity and lung disease. Environ Health Perspec 1989; 81: 91–94.
8. Broaddus, V.C., Yang, L., Scavo, L.M., Ernst, J.D., Boylan, A.M. Crocidolite asbestos in-
duces apoptosis of pleural mesothelial cells – role of reactive oxygen species and poly(adp-
ribosyl) polymerase. Environ Health Perspec 1997; 105: 1147–1152.
9. Walker, C., Everitt, J., Barrett, J.C. Possible cellular and molecular mechanisms for asbes-
tos carcinogenicity. Am J Ind Med 1992; 21: 253–273.
10. Broaddus, V.C., Yang, L., Scavo, L.M., Ernst, J.D., Boylan, A.M. Asbestos induces apoptosis
of human and rabbit pleural mesothelial cells via reactive oxygen species. J Clin Invest
1996; 98: 2050–2059.
11. Gabrielson, E.W., Van der Meeren, A., Reddel, R.R., Reddel, H., Gerwin, B.I., Harris, C.C.
Human mesothelioma cells and asbestos-exposed mesothelial cells are selectively resis-
tant to amosite toxicity: a possible mechanism for tumor promotion by asbestos. Carcino-
genesis 1992; 13: 1359–1363.
12. Yegles, M., Saint-Etienne, L., Renier, A., Janson, X., Jaurand, M.C. Induction of metaphase
and anaphase/telophase abnormalities by asbestos fibers in rat pleural mesothelial cells in
vitro. Am J Respir Cell Mol Biol 1993; 9: 186–191.
13. Kinnula, V.L., Pietarinenruntti, P., Raivio, K., et al. Manganese superoxide dismutase in
human pleural mesothelioma cell lines. Free Radic Biol Med 1996; 21: 527–532.
14. Fung, H., Kow, Y.W., Vanhouten, B., et al. Asbestos increases mammalian ap-endonuclease
gene expression, protein levels, and enzyme activity in mesothelial cells. Cancer Res 1998;
58: 189–194.
15. Kinnula, K., Linnainmaa, K., Raivio, K.O., Kinnula, V.L. Endogenous antioxidant enzymes
and glutathione S-transferase in protection of mesothelioma cells against hydrogen per-
oxide and epirubicin toxicity. Br J Cancer 1998; 77: 1097–1102.
16. Carbone, M., Pass, H.I., Rizzo, P., et al. Simian virus 40-like DNA sequences in human
pleural mesothelioma. Oncogene 1994; 9: 1781–1790.
1. Wagner, J.C., Sleggs, C.A., Marchand, P. Diffuse pleural mesothelioma and asbestos expo-
sure in the North Western Cape Province. Br J Ind Med 1960; 17: 260–271.
2. Hansen, J., Deklerk, N.H., Musk, A.W., Hobbs, M.S.T. Environmental exposure to crocido-
lite and mesothelioma – exposure-response relationships. Am J Respir Crit Care Med 1998;
157: 69–75.
3. McDonald, J.C., McDonald, A.D. The epidemiology of mesothelioma in historical context [Review]. Eur Respir J 1996; 9: 1932–1942.
4. Branchaud, R.M., Garant, L.J., Kane, A.B. Pathogenesis of mesothelial reactions to asbes-
tos fibres. Monocyte recruitment and macrophage activation. Pathobiology 1993; 61: 154–
163.
5. Owens, M.W., Grimes, S.R. Pleural mesothelial cell response to inflammation: tumor ne-
crosis factor-induced mitogenesis and collagen synthesis. Am J Physiol 1993; 265: L382–
388.
6. Davis, J.M. Ultrastructure of human mesotheliomas. J Natl Cancer Inst 1974; 52: 1715–
1725.
7. Mossman, B.T., Marsh, J.P. Evidence supporting a role for active oxygen species in asbes-
tos-induced toxicity and lung disease. Environ Health Perspec 1989; 81: 91–94.
8. Broaddus, V.C., Yang, L., Scavo, L.M., Ernst, J.D., Boylan, A.M. Crocidolite asbestos in-
duces apoptosis of pleural mesothelial cells – role of reactive oxygen species and poly(adp-
ribosyl) polymerase. Environ Health Perspec 1997; 105: 1147–1152.
9. Walker, C., Everitt, J., Barrett, J.C. Possible cellular and molecular mechanisms for asbes-
tos carcinogenicity. Am J Ind Med 1992; 21: 253–273.
10. Broaddus, V.C., Yang, L., Scavo, L.M., Ernst, J.D., Boylan, A.M. Asbestos induces apoptosis
of human and rabbit pleural mesothelial cells via reactive oxygen species. J Clin Invest
1996; 98: 2050–2059.
11. Gabrielson, E.W., Van der Meeren, A., Reddel, R.R., Reddel, H., Gerwin, B.I., Harris, C.C.
Human mesothelioma cells and asbestos-exposed mesothelial cells are selectively resis-
tant to amosite toxicity: a possible mechanism for tumor promotion by asbestos. Carcino-
genesis 1992; 13: 1359–1363.
12. Yegles, M., Saint-Etienne, L., Renier, A., Janson, X., Jaurand, M.C. Induction of metaphase
and anaphase/telophase abnormalities by asbestos fibers in rat pleural mesothelial cells in
vitro. Am J Respir Cell Mol Biol 1993; 9: 186–191.
13. Kinnula, V.L., Pietarinenruntti, P., Raivio, K., et al. Manganese superoxide dismutase in
human pleural mesothelioma cell lines. Free Radic Biol Med 1996; 21: 527–532.
14. Fung, H., Kow, Y.W., Vanhouten, B., et al. Asbestos increases mammalian ap-endonuclease
gene expression, protein levels, and enzyme activity in mesothelial cells. Cancer Res 1998;
58: 189–194.
15. Kinnula, K., Linnainmaa, K., Raivio, K.O., Kinnula, V.L. Endogenous antioxidant enzymes
and glutathione S-transferase in protection of mesothelioma cells against hydrogen per-
oxide and epirubicin toxicity. Br J Cancer 1998; 77: 1097–1102.
16. Carbone, M., Pass, H.I., Rizzo, P., et al. Simian virus 40-like DNA sequences in human
pleural mesothelioma. Oncogene 1994; 9: 1781–1790.
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